Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1987-10-20
1989-06-06
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 51, 424451, 424464, 536 23, A61K 3170, A61K 900, A61K 922
Patent
active
048372080
ABSTRACT:
Treatment of AIDS or humans carrying or infected with the AIDS virus or having antibodies to the AIDS virus is disclosed using the compound 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof.
Also disclosed is the use of the 5'-mono-, di- and triphosphate of 3'-azido-3'-deoxythymidine or a pharmaceutically acceptable basic salt thereof for the same purpose.
REFERENCES:
Krieg et al., Exp Cell Res. 116:21-29, 1978.
Lin et al., J. Med. Chem. 26:1691-1696, 1983.
De Clercq et al., Biochem Pharm. 29:1849-1851, 1980.
Barry David W.
Furman Phillip A.
Lehrman Sandra N.
Rideout Janet L.
St. Clair Martha H.
Brown Donald
Burroughs Wellcome Co.
Nielsen Lawrence A.
Rollins John W.
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