Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-04-16
1999-08-17
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514 2, 514 12, A61K 3152
Patent
active
059394234
ABSTRACT:
Treatment of hepatitis B virus (HBV) infection in a patient by administering to the patient a drug regimen including an antiviral-effective amount of thymosin alpha 1 (T.alpha.1) and an antiviral-effective amount of famciclovir.
REFERENCES:
patent: 5308833 (1994-05-01), Scharschmidt
De Man et al. Scand. J. Gastroenterol. 30(Suppl. 212) 100-104, Jan. 1995.
Andreone P et al. Hepatology 24 (4), 774-777, Apr. 1996.
Database Investext 97:519492 Report Number: 1904847 Sciclone Pharmaceuticals, Inc. Company Report, May 1997.
Database Investext Report Number:1293001. Biotechnology--Industry Report, Jan. 1993.
Marinos et al. Hepatology, 24, 991-995, Apr. 1996.
Doctors Guide to Medical and Other News, "Famvir is Safe and Effective for Treatment of Hepatitis B", Chicago, Nov. 11, 1996, http://www.psIgroup.com/dg/daae.htm.
ALF Progress Index, Hepatitis B Drug Studies, "Two Promising Drugs" Under Study for Hepatitis B, American Liver Foundation, 1425 Pompton Avenue, Cedar Grove, NJ 07009, http://sadieo.ucsf.edu/ALFfinal/proghepbdrugs.html. (Date not available.
"Chronic Hepatitis B Virus Infection Phase I-II Treatment Study", Protocol: 95-1-0062, Dr. Adriana Marques, Building 10, Room IIN228, 10 Center Dr MSC 1888, Bethesda, MD 20892, http://www.niad.nih.gov/recruit/hepb.htm. (Date is unavailable).
TT Aye. Al Bartholomeusz et al., "Hepatitis B virus polymerase mutations during famciclovir therapy in patients following liver transplatation", VIDRL Publications, http:hna.ffh.vic.gov.au/vidrl...bstr.sub.- 96/abstr.sub.- aye.sub.- hbmut.sub.- 96.html. (Date is unavailable).
TT Aye. Al Bartholomeusz et al., "Hepatitis B virus polymerase mutations induced by famciclovir therapy", VIDRL Publications, http://hna.ffh.vic.gov.au/vidrl...str.sub.- 96/abstr.sub.- aye.sub.- hbpoly.sub.- 96.html. (Date unavailable).
CenterWatch Study Information (10), Trial Information, Summary: Study of an investigational treatment for HbeAg+ chronic hepatitis B, Libby Behler/Ingrid Crause, Study Contacts, University of Michigan, GCR, 3912 Taubman Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-0362,http://www.centerwatch.com/STU989.HTM. (Date unavailable).
Penciclovir/famciclovir (SmithKline-Beecham) shows promise against duck HBV and was used succesfully for "compassionate" reasons with two patents in Australia (reported at the international Antiviral Meeting, Charleston, S.C. Mar. 1994).
Karlin David Alan
Porter Steven L.
Borin Michael
SciClone Pharmaceuticals Inc.
Tsang Cecilia J.
LandOfFree
Treatment of hepatitis B infection with thymosin alpha 1 and fam does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of hepatitis B infection with thymosin alpha 1 and fam, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of hepatitis B infection with thymosin alpha 1 and fam will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-315003