Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Fungus – except allergen – or component thereof or substance...
Patent
1976-03-23
1978-07-11
Schenkman, Leonard
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Fungus, except allergen, or component thereof or substance...
424317, 424319, A61K 3140, A61K 3119, A61K 31195
Patent
active
041002938
ABSTRACT:
Treatment of hepatic disorders, such as are characterized by hyperammonemia and portal-systemic encephalopathy, is advocated using compositions comprising keto analogs of certain essential amino acids. In the preferred embodiments, such compositions comprise the keto analogs of valine, phenylalanine, methionine, leucine and isoleucine.
REFERENCES:
patent: 2457820 (1949-01-01), Howe et al.
patent: 3764703 (1973-10-01), Bergstrom et al.
Chemical Abstracts 81:54452q (1974).
Chemical Abstracts 82:144958j (1975).
Richards et al., Lancet pp. 128-134 (Jul. 17, 1971), pp. 845-849 (Oct. 21, 1967).
Rudman, J. of Clincial Invest. 50, pp. 90-96 (1971).
Schenkman Leonard
The Johns Hopkins University
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