Treatment of Helicobacter with isothiocyanates

Details Treatment of Helicobacter with isothiocyanates Treatment of Helicobacter with isothiocyanates

2008-07-22

2008-07-22

Kwon, Brian-Yong S (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S514000, C514S023000

Reexamination Certificate

active

10813015

ABSTRACT:
The present invention relates to methods of preventing or inhibiting the growth ofHelicobacterthrough the use of a composition that comprises a glucosinolate, an isothiocyanate or a derivative or metabolite thereof. The present invention also relates to methods of preventing or treating persistent chronic gastritis, ulcers and/or stomach cancer in subjects at risk for, or in need of treatment thereof.

REFERENCES:
patent: 5114969 (1992-05-01), Chung et al.
patent: 5411986 (1995-05-01), Cho et al.
patent: 5589504 (1996-12-01), Dannenberg et al.
patent: 5725895 (1998-03-01), Fahey et al.
patent: 5968505 (1999-10-01), Fahey et al.
patent: 5968567 (1999-10-01), Fahey et al.
patent: RE36784 (2000-07-01), Cho et al.
patent: 6177122 (2001-01-01), Fahey et al.
patent: 6340784 (2002-01-01), Mithen et al.
patent: 6348220 (2002-02-01), Ribnicky et al.
patent: 6465512 (2002-10-01), Nakamura et al.
patent: WO 97/26908 (1997-07-01), None
Alain Lozniewski, et al. “Human Embryonic Gastric Xenografts in Nude Mice: a New Model ofHelicobacterpyloriInfection,”Infection And Immunity(Apr. 1999) 67(4):1798-1805, American Society for Microbiology.
Haim Shirin et al., “Helicobacter pyloridecreases gastric mucosal glutathione,”Cancer Letters.(Mar. 2001) 164:127-133 Elsevier Science Ireland Ltd.
Yuesheng Zhang et al., “A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure,”Proc. Natl. Acad. Sci.(Mar. 1992) 89:2399-2403 (Mar. 1992).
G. Roger Fenwick et al., “Glucosinolates and Their Breakdown Products in Food and Food Plants,”CRC Crit. Rev. Food Sci. Nutr.(1983) 18:123-201, CRC Press.
Jan Jorn Hansen et al., “Intramolecular Cyclizations of Thioureas Derived from Sulphoraphene: a Case of Asymmetrically Induced Additions to Vinylic Sulphoxides,”Acta Chemica Scandinavica B.(1974) 28(4):418-424 Chemical Societies in Denmark, Finland, Norway and Sweden.
Kurt Mislow et al., “Optical Rotatory Dispersion and Absolute Configuration of Dialkyl Sulfides,”Journal of the American Chemical Society.(Feb. 1965) 87(3): 665-666.
Jed W. Fahey et al., “The cheical diversity and distributin of glucosinolates and isothiocyanates among plants,”Phytochemistry(Jan. 2001) 56:5-51 Elsevier Science Ltd.
Database WPI, Section Ch, Week 198632 Derwent Publications Ltd., London, GB; AN 1986-209527; XP002198443 & JP 61 143353 A (Denki Kagaku Kogyo KK), Jul. 1, 1986 abstract only.
Zhang et al., :Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Database Medline ′Online! Apr. 1, 1994; database accsssion No. NLM8137323, XP002198442 abstract & Cancer Research, vol. 54, No. 7 Suppl., Apr. 1, 1994 pp. 1976s-1981s, ISSN: 0008-5472.
Fahey et al., “Antioxidant Functions of Sulforaphane: a Potent Inducer of Phase II Detoxication Enzymes,”Food and Chemical Toxicology:37:973-979 (1999) ISSN: 0278-6915.

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