Treatment of growth hormone deficiency

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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514 21, 424479, 530324, 530395, 530399, A61K 3800, A61K 3824, A61K 950

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active

058519920

ABSTRACT:
A pharmaceutical formulation comprising a growth hormone and asparagine as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds. The stability of the product allows for the storing and shipment thereof in a lyophilized state or in the form of a dissolved or re-dissolved preparation at ambient temperature. The formulation may be used to treat a patient with a disorder associated with growth hormone deficiency.

REFERENCES:
patent: 4816568 (1989-03-01), Hamilton, Jr. et al.
patent: 4917685 (1990-04-01), Viswanathan et al.
patent: 5547696 (1996-08-01), Sorensen
patent: 5552385 (1996-09-01), Christensen et al.
Johnson et al., The Journal of Biological Chemistry, vol. 264, No. 24, pp. 14262-14271, 1989.
Ottaway, Biochem. J., vol. 136 pp. 441-444, 1973.
Ottaway, Biochem. J., vol. 129, pp. 503-505, 1972.
Wang et al., J. Parent. Sci. & Tech., vol. 42, pp. S3-S26 (1988).
Manning et al., Pharmaceutical Research, vol. 6, No. 11, pp. 903-918 (1989).
Johnson et al., The Journal of Biological Chemistry, vol. 264, No. 24, pp. 14262-14271 (1989).
Teh et al., J. of Biol. Chem., vol. 262, No. 14, pp. 6572-6477 (1987).
Becker et al., Biotech. and App. Biochem., vol. 10, pp. 326-337 (1988).
Houghten et al., Arch. of Biochem. Biophysics, vol. 178, pp. 350-355 (1977).
Riggen et al., Analytical Biochem., vol. 167, pp. 199-209 (1987). 93-100 (1990).
Kaufman, Pharmaceutical Research, vol. 7. No. 3, pp. 289-292 (1990).
Becker et al., Biotech, and Applied Biochem., vol. 9, pp. 478-487 (1987).
Jensen et al., Biotech. and Bioengineering, vol. 36, No. 1, p. 1-11. 1990.

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