Treatment of gastrointestinal disorders

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514183, 514210, 514212, 514277, 514294, 514295, 514296, 514299, 514305, 514319, 514320, 514323, 514324, 514408, 514413, 514414, 514415, 514428, A61K 3134, A61K 3138, A61K 31405, A61K 31435

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active

049101935

ABSTRACT:
Use of a mono or dicyclic carboxylic or heterocyclic carboxylic acid ester or amide of an alcohol or amine nitrogen as a ring atom in free base form or in acid addition or quaternary ammonium salt form as a 5-HT.sub.3 antagonist in the manufacture of a medicament suitable for the treatment of serotonin induced gastrointestinal disturbances.

REFERENCES:
patent: 2857383 (1958-10-01), Voegtli
patent: 3838169 (1974-09-01), Thominet
patent: 4141884 (1979-02-01), Irick, Jr. et al.
patent: 4182703 (1980-01-01), Irick, Jr. et al.
patent: 4721720 (1988-01-01), Wootton et al.
patent: 4725603 (1988-02-01), Sanger et al.
Chem. Abstracts; vol. 100; No. 209629q.
Meeting of British Pharm. Society, Abstract No. 52, Apr. (1986).

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