Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1995-06-07
2000-07-25
Bockelman, Mark
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
604288, A61M 3100
Patent
active
060931817
ABSTRACT:
Erectile dysfunction, particularly impotence, priapism and Peyronie's disease is treated by the transurethral administration of a therapeutically effective agent. The agents are administered to the urethra by means of a penile insert (1) having a rapidly releasing coating (4) containing the agent on its exterior surface or by means of an inserter (27) carrying an agent containing dose of agent (31) which can be displaced into the urethra.
REFERENCES:
patent: 4127118 (1978-11-01), Latome
patent: 4801587 (1989-01-01), Voss et al.
patent: 5236904 (1993-08-01), Gerstenberg et al.
patent: 5256652 (1993-10-01), El-Rashidy
patent: 5399581 (1995-03-01), Laragh
patent: 5482039 (1996-01-01), Place
patent: 5492911 (1996-02-01), Stief
patent: 5843961 (1998-12-01), Kock et al.
patent: 5849803 (1998-12-01), Kock et al.
patent: 5886039 (1999-03-01), Kock et al.
Owen, J.A., et al., "Topical Nitroglycerin: A Potential Treatment for Impotence", Journal of Urology 141:546-548 (1989).
Malloy, T.R., et al., "Pharmacological treatment of impotence", Urologic Clinics of North America 14(2):297-305 [see 303-304] (1987).
Klinge, E., et al., "Comparative study of some isolated mammalian smooth muscle effectors of penile erection", Acta Physiol. Scand., vol. 100:354-67 (1977).
Barbanti, G., et al., "Relaxation of isolated corpus cavernosum induced by smooth muscle relaxant drugs", Urol. Res., vol. 16(4):299-302 (1988).
Ahmad, S., "Scleroderma and impotence: Response to nitroglycerin applied to the fingers and penis", South Med. J. 83:1495 (1990).
Talley, J.D., et al., "Transdermal nitrate, penile erection and spousal headache", Ann. Intern. Med. 103:804 (1985).
Yamamura, K.,et al., "High-Performance Liquid Chromatographic Assay for Prostaglandin E1 in Various Ointment Vehicles", J.Chromatography 303:165-172 (1984).
Sundaram, M.B.M., "Seizures After Intraurethral Instillation of Lidocaine," Canad. Med. Assn. J. 137:219-220 (1987).
Robinette, M.A., et al., "Intracorporal Injection of Papaverine and Phentolamin in the Management of Impotence", Br. J. Urology 58:692-695 (1986).
Heaton, J.P.W., et al., "Topical glyceryltrinitrate causes measurable penile arterial dilation in impotent men.", J. Urology 143:729-731 (1990).
Claes, H., et al., "Transcutaneous Nitroglycerin Therapy in the Treatment of Impotence", Urol. Int., 44:309-312 (1989).
Zorgniotti, A.W., et al., "Auto-injection of the Corpus Cavernosum with a Vasoactive Drug Combination for Vasculogenic Impotence" J. Urol., 133:39-41 (1985).
Rudd., et al., The Pharmacological Basis of Therapeutics, Gilman et al. (Eds) 7th Ed., Chap. 32 pp. 784-785 (1985).
Turner, J.E., et al., "Prostaglandin E.sub.2 in Tylose Gel for Cervical Ripening Before Induction of Labor", J. Reprod. Med., 32(11):815-821 (1987).
Andersson, K.E., et al., "Effects of Prostaglandin E.sub.2 Applied Locally on Intravesical and Intraurethral Pressure in Women", Eur. Urol., 4(5):366-369 (1978).
Axelsson, K., et al., "Blood Concentration of Lignocaine after Application of 2% Lignocaine Gel in the Urethra", Br. J. Urol., 55(1):64-68 (1983).
Owen, J., et al., "Transcutaneous Nitroglycerine Enhances the Quality of Erections in Impotent Men. Results of a Controlled Trial", J. Urol., 137, 201A, abstract 392 (1987).
Anonymous, "Intracavernous injections for impotence", The Medical Letter, 751:39.95 (1987).
Brindley, G.S., "Cavernosal alpha-blockage: A new technique for investigating an treating erectile impotence", Brit. J. Psychiatr., 143:332-377 (1983).
Brindley, G.S., "Pilot experiments on the actions of drugs injected into the human corpus cavernosum penis", Br. J. Pharmacol, 87:495-500 (1986).
Ishii, N., et al., "Studies on male sexual impotence. Report 18. Therapeutic trial with prostaglandin E1 for organic impotence", 77:954-962 (1986).
Stackl, W., et al., "Intracavernous injection o prostaglandin E1 in impotent men", J. Urol., 140:66-68 (1988).
Virag, R., "Intracavernous injection of papverine for erectile failure" [letter], Lancet, 2:938 (1982).
Berggren Randall G.
Gale Robert M.
Place Virgil A.
Bockelman Mark
Hartrum J. Elin
Reed Dianne E.
Vivus Inc.
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