Treatment of equine laminitis

Details Treatment of equine laminitis Treatment of equine laminitis

1996-11-19

1999-04-06

Levy, Neil S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

424485, 514645, 514509, 514946, 514947, A61K 906

Patent

active

058914722

ABSTRACT:
Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID mixed in a lipid-based carrier are described. The application of such combinations to the affected areas, e.g., the hoofs and surrounding tissues, of an equine afflicted with laminitis provides relief from the debilitating effects of this painful, often life-threatening condition.

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Green, M. E. et al. (Author) "LAMINITIS", Chapter 12, pp. 1354-1358, Equine Medicine and Surgery, Fourth Edition, vol. II, Colahan, P. T. et al. (Eds.), American Veterinary Publications, Inc. (1991).
"Lecithin Organogel as Matirx for Transdermal Transport of Drugs", Journal of Pharmaceutical Sciences, Willimann et al., vol. 81, No. 9, Sep. 1992, pp. 871-874.
"Nitric Oxide Donors as Treatment for grass Induced Acute Laminitis in Ponies", Equine Veterinary Journal, Hinckley et al., vol. 28(1), 1996, pp. 17-28.

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