Treatment of endometriosis

Details Treatment of endometriosis Treatment of endometriosis

1991-04-11

1992-11-24

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514180, 514178, A61K 3156

Patent

active

051662000

ABSTRACT:
A remedy for endometriosis comprising, as an active ingredient, 14.alpha.-hydroxy-4-androstene-3,6,17-trione or an ester derivative thereof, can effectively treat endometriosis by the strong aromatase-inhibitory activity without giving serious side effects.

REFERENCES:
Patent Abstracts of Japan, vol. 13, No. 379 (C-628)[3727]Aug. 22, 1989.
Yamamoto et al., "Inhibitory Effect of a New Androstenedione Derivative, 14.alpha.-hydroxy-4-Androstene-3,6,17-Trione (14.alpha.-OHAT) on Aromatase Activity of Human Uterine Tumors," J. Steroid Biochem., vol. 36, No. 6, pp. 517-521 (1990).
Dictionnaire des Termes Techniques de Medecine, 20th ed., pp. 414-415 (1983).
CA: 110(21)-191258n-Yoshihama et al. (May 1989).
CA: 110(23)-2148112-Nakakoshi et al. (Dec. 1989).

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