Treatment of Dutch elm disease

Details Treatment of Dutch elm disease Treatment of Dutch elm disease

1998-03-26

2000-08-29

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514 13, 514 2, 530322, 530324, 530325, 530395, A61K 3814

Patent

active

061108901

ABSTRACT:
A preventative treatment for Dutch elm disease is disclosed which provides susceptible elm trees with induced resistance to Dutch elm disease-causing fungi such as Ophiostoma ulmi. The treatment comprises administering to a susceptible elm tree an amount of an elicitor effective to cause a defence reaction in the tree. The defence reaction comprises a cascade of events including accumulation by the tree of mansonones, which are sesquiterpene quinones having antifungal properties. The preferred elicitor for use as a treatment for Dutch elm disease is a novel elicitor isolated from cultures of O. ulmi. The preferred elicitor is non-toxic and heat stable and is shown to be effective for inducing resistance to Dutch elm disease in susceptible elm trees.

REFERENCES:
patent: 4075327 (1978-02-01), Jorgensen et al.
patent: 4078087 (1978-03-01), Hyman
patent: 4277462 (1981-07-01), Strobel
patent: 4342746 (1982-08-01), Strobel
patent: 4377571 (1983-03-01), Strobel
patent: 4814331 (1989-03-01), Kerkenaar
patent: 4886664 (1989-12-01), Jung et al.
patent: 4886671 (1989-12-01), Cryer
Yang, D.Q., "Isolation, Identification and Characterization of Phytoalexin, Elicitors from Ophiostoma Ulmi". Diss: Abstr. Int. B 1992, 53(2), 634 (Abstract Only).
M.T. Dumas et. al.: "Inhibition of Ceratocystis ulmi by Mansonones A, C, D, E, F, and G isloated from Ulmus americana" Eur. J. for Pathol., vol. 16, No. 4, 1986, pp. 217-222.
L.C. Duchesne et. al., "Mansonone E and F accumulation in Ulmus pumila resistant to Dutch elm disease" Can. J. For Res., vol. 16, No. 2, 1986, pp. 410 to 412.
R.S. Jeng et al., "Presence and accumulation of fungitoxic substances against Ceratocystis ulmi in Ulmus americana: possible relation to induced resistance" Eur. Journal of Forest Pathology, vol. 13, No. 4, 1983, pp. 239-244.
L. Bernier et. al., "Assessment of Phaeotheca dimorphospora for biological control of the Dutch elm disease pathogens, Ophiostoma ulmi and O. novo-ulmi." Plant Pathol., vol. 45, No. 4, 1996,pp. 609-617.
W.D. Wu, et al.,: "Toxic Effects of Elm Phytoalexin Mansonones on Ophiostoma ulmi, the Causal Agent of Dutch Elm Disease", Eur. J. for Path. vol. 19,No. 5, 6 1989.
L.C. Duchesne et al., "Accumulation of Phytoalexins in Ulmus americana in Response to Infection by a Nonaggressive and a aggressive Strain ofOphiostoma ulmi",; Can J. Bot., vol. 63,, No.4, 1985, pp. 678-680.
R.S. Jeng et al., "Isolation and ultrastructural localization of a soluble protein from Ophiostoma ulmi", Can. J. Bot., vol. 68, No. 11, 1990, pp. 2517-2524.
Dumas et al., "Isolation and identification of six mansonones from Ulmus americana . . . ", Experientia 39 (1983) pp. 1089-1090.
Hubbes, "Pathogen Virulence and Host Reaction in Dutch Elm Disease", Naturaliste can. (Rev. Ecol. Syst.), 115: 157-161 (1988).
Yang et al., "Factors influencing mansonone induction in elm cells . . . ", Eur. J. For. Path. 23 (1993) 257-268.
Yang et al., "Mansonone accumulation in elm callus induced by . . . ", Can. J. Bot. vol. 67, 1989, pp. 3490-3497.
Jeng et al., "Mitochondrial DNA restriction fragment length . . . ", Mycol. Res. 95(5): 537-542 (1991).
Hubbes, "Influence of biotechnology on forest disease research and . . . ", Canadian Journal of Plant Pathology 9: 343-348, 1987.
Hubbes, "Terpenes and unsaturated fatty acids trigger coremia . . . ", Eur. J. For. Path. 5 (1975) 129-137.
Bernier et al., "Induction and genetic characterization of . . . ", Mycol. Res. 98(8), 943-953 (1994).
Jeng et al., "A comparison of the nucleotide sequence of the . . . ", Curr Genet (1996) 29: 168-173.
Sutherland et al., "Control of Dutch elm disease by induced host resistance", Eur. J. For. Path. 25 (1995) 307-318.
Svircev et al., "Detection of Cerato-Ulmin on Aggressive Isolates . . . ", Phytopathology vol. 78, No. 3, 1988, pp. 322-327.
Hubbes et al., "Aggressiveness of Ceratocystis ulmi strains and . . . ", Eur. J. For. Path. 11 (1981) 257-264.
Yang et al., "A glycoprotein isolated from culture filtrates of . . . ", Mycol. Res. 98(3): 295-300 (1994).

Affiliated with

Also associated with

Rating

Treatment of Dutch elm disease does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Treatment of Dutch elm disease, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of Dutch elm disease will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1249922