Treatment of disparate bleeding disorders with factor X zymogen

Details Treatment of disparate bleeding disorders with factor X zymogen Treatment of disparate bleeding disorders with factor X zymogen

1983-06-27

1985-02-26

Rosen, Sam

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

A61K 3516

Patent

active

045017310

ABSTRACT:
The invention provides a method for the treatment of disparate bleeding disorders comprising the administration of factor X zymogen in amounts sufficient to control pathological bleeding, and a therapeutic product based on the coagulant activity of a factor X zymogen-phospholipid-factor Va clotting system. The product is generally substantially free of activators for the factor X zymogen.

REFERENCES:
patent: 4382083 (1983-05-01), Thomas
Hoffbrand et al., Recent Advances in Haematology, No. 2, (1977), pp. 431-434.
Nemerson et al., "Zymogens and Cofactors of Blood Coagulation", 1980, pp. 45-85.
DiScipio et al., Biochem., vol. 16, No. 4, (1977), pp. 698-706, "A Comparison of Human Prothrombin, Factor IX, etc.".
Esnouf, "Haemostesis", edited by Ogston & Bennett, J. Wiley & Sons, N.Y., Ch. 4, 1977, pp. 78-85.
Hilgartner et al. Blood, 61:36-40, 1983.
Liesbeth et al., New Eng. J. Med. 305:717-721, 1981.
Lusher et al., New Eng. J. Med. 303:421-425, 1980.
Prowse et al., Thrombos. Haemostas 42:1355-1367, 1979.
Aronson, Seminars in Thrombosis and Hemostatis, 6:28-43, 1979.
Menache, Thrombos. Diathes. Haemorrh., 33:600-605, 1975.
Chandra et al., Throm. Res. 12:571-582, 1978.
Barrowcliffe et al., Vox Sang. 25:426-441, 1973.
Suomela et al., Vox Sang. 32;1-16, 1977.
Subbaiah et al., Biochem. Biophys. Acta. 444:131-146, 1976.
Nesheim et al., J.B.C. 254:10952-10962, 1979.
Tishkoff, N.E.J. Med. 292:754-755, 1975.
Tishkoff, Thrombosis et Diathesis Hemorrhagica, 34:589, 1975.
Tishkoff, Published Report, pp. 103-110, (1976).
Elsinger, Published Report, pp. 77-87, 1982.
Elsinger, Published Report, pp. 1-9, World Fed. of Hemophilia, 1977.
Barrowcliffe et al., J. Lab. Clin. Med. 101:34-43, 1983.
Elsinger, Published Report, pp. 101-103, 1976.

Affiliated with

Also associated with

Rating

Treatment of disparate bleeding disorders with factor X zymogen does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Treatment of disparate bleeding disorders with factor X zymogen, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of disparate bleeding disorders with factor X zymogen will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-516367