Treatment of disorders associated with pulmonary hypertension an

Details Treatment of disorders associated with pulmonary hypertension an Treatment of disorders associated with pulmonary hypertension an

1988-07-05

1991-07-16

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514422, 514456, A61K 3135, A61K 3140, A61K 3144

Patent

active

050325965

ABSTRACT:
A method for the treatment and/or prophylaxis of disorders associated with pulmonary hypertension and/or disorders associated with right heart failure, in mammals, which method comprises administering to the mammal in need of such treatment and/or prophylaxis an effective and/or prophylactic, non-toxic, amount of a compound of formula (I): ##STR1## wherein A.sup.1 represents CR.sub.1, N or N.sup.+ --O.sup.- ; when A.sup.1 represents N or N.sup.+ --O.sup.-, R.sup.2 represents hydrogen;

REFERENCES:
patent: 4738963 (1988-04-01), Hamilton et al.
patent: 4772603 (1988-09-01), Evans
patent: 4782083 (1988-11-01), Cassidy et al.
patent: 4786639 (1988-11-01), Evans
patent: 4812459 (1989-03-01), Evans et al.

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