Treatment of diseases mediated by the nitric oxide/cGMP/protein

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – C-o-group doai

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514724, 514739, A61K 31045

Patent

active

059901772

ABSTRACT:
Disclosed are methods and compositions for stimulating cellular nitric oxide (NO) synthesis, cyclic guanosine monophosphate levels (cGMP), and protein kinase G (PKG) activity for purposes of treating diseases mediated by deficiencies in the NO/cGMP/PKG signal transduction pathway, by administration of various compounds including alcohols, diols and/or triols and their analogues.

REFERENCES:
patent: 5747532 (1998-05-01), Lai
Merck Index, 10th Edn, # 1708, 2696, 3744, 7756, 9522, 1983.

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