Treatment of congestive heart failure

Chemistry: molecular biology and microbiology – Maintaining blood or sperm in a physiologically active state...

Reexamination Certificate

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Reexamination Certificate

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07153649

ABSTRACT:
A method of treating congestive heart failure (CHF) in a human patient comprises treating an aliquot of the patents blood ex vivo with at least one stressor selected from the group consisting of a temperature above or below body temperature, an electromagnetic emission and an oxidative environment, followed by administering the aliquot of treated blood to the patient. The treatment can be used on its own or as an adjunctive therapy in combination with conventional CHF treatments.

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patent: WO 00/67764 (2000-11-01), None
Cooke, E.D., et al. “Treatment of severe Raynaud's syndrome by injection of autologous blood pretreated by heating, ozonation and exposure to ultraviolet light (H-O-U) therapy.”International Angiology. 16(4): 250-254 (1997).
Dibbs, Z., et al. “Cytokines in Heart Failure: Pathogenetic Mechanisms and Potential Treatment.”Proceedings of the Association of American Physicians. 111(5): 423-428 (1999).
Ganelina, I.E., et al. “Therapy of Severe Steno Cardias by UV Irradiation of the Blood and Some Action Mechanisms of this Therapy.”Folia Haematologica. 109(3): 470-482 (1982).
Mann, D.L., et al. “Mechanisms and Models in Heart Failure: A Combinatorial Approach.”Circulation. 100: 999-1008 (1999).

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