Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1994-08-02
1997-08-26
Jordan, Kimberly
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514423, A61K 3800, A61K 3140
Patent
active
056611226
ABSTRACT:
Methods of enhancing myocardial contractility and cardiac performance in a mammal with congestive heart failure are disclosed. In a first method a mammal with congestive heart failure is treated by administering to the mammal an effective amount of a combination of growth hormone (GH) and insulin-like growth factor (IGF-I). A second method comprises administering to the mammal an effective amount of a combination of GH and IGF-I in the presence of an ACE inhibitor. This method results in enhancement of myocardial contractility and cardiac performance above the level achieved with ACE inhibition alone. Preferably the mammal is a human.
REFERENCES:
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Clark Ross G.
Jin Hongkui
Paoni Nicholas F.
Yang Renhui
Dreger Walter H.
Genentech Inc.
Hasak Janet E.
Jordan Kimberly
LandOfFree
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