Treatment of colon cancer

Details Treatment of colon cancer Treatment of colon cancer

2005-02-08

2005-02-08

Richter, Johann R. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C560S008000, C560S019000, C560S047000, C560S038000, C560S043000, C560S101000, C560S117000, C560S121000, C560S156000, C560S205000, C560S219000

Reexamination Certificate

active

06852876

ABSTRACT:
The novel compound of the disclosure is 4-chloro-4-(4-ethoxy-phenyl)-2-(fluoren-9-ylidene-hydrazono)-but-3-enoic acid methyl ester (3F-19), and it alone or in combination with 4-(4-Ethoxy-phenyl)-2-(N′-fluoren-9-ylidene-hydrazino)-2-hydroxy-4-oxo-butyric acid methyl ester (OF-13), appears useful in humans as therapeutic means for the eradication of tumors from the human's colon.

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“Cyclization of Chloro 2,3-diazahexa-1,3,5-triene to 1-chloromethylpyrozole With [1,3] Migration of the Chlorine Atom”, in Chemistry of Heterocyclic Compounds, vol. 37, No. 6, 2001, as traslated from Khimiya Geterosiklicheskikh Soedinenii, No. 6, pp. 843-848.

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