Treatment of chronic obstructive pulmonary disease (COPD) by inh

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514402, 514826, 514851, 424 45, A61K 31415, A61L 904

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active

050969161

ABSTRACT:
A method of using an imidazoline compound, which is a vasodilator and an alpha-adrenergic blocking agent, for the treatment of symptoms of chronic obstructive pulmonary diseases (COPD), including cystic fibrosis, chronic bronchitis and emphysema, or COPD where it is associated with asthma, comprises administering the imidazoline to a patient by inhalation. Preferably, the imidazoline compound employed is tolazoline. The presentation of an imidazoline compound in a device for the administration of an aerosol is disclosed.

REFERENCES:
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Barnes et al., J. of Allergy and Clinical Immunology, 68, 411 (1981).
Cotton, E. K., "Tolazoline in the Treatment of Cystic Fibrosis", The Society for Pediatric Research Program and Abstracts of the 36th Annual Meeting, p. 51, (1966).
Cotton, E. K., "Tolazoline in the Treatment of Cystic Fibrosis", The Society for Pediatric Research Program and Abstracts of the 36th Annual Meeting, p. 51, (1966).

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