Treatment of chronic diffuse GI bleeding with erythropoietin

Details Treatment of chronic diffuse GI bleeding with erythropoietin Treatment of chronic diffuse GI bleeding with erythropoietin

1998-02-04

1999-09-14

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

424350, A61F 202, C07K 14505

Patent

active

059519967

ABSTRACT:
A method for the treatment of diffused GI bleeding by the subcutaneous administration of erythropoietin. The method is suitable for patients with radiation induced proctitis or diffused angiodysplasia of the colon, and makes unnecessary the need for the removal of portions of the GI track. Continuation of the administration of erythropoietin is necessary to avoid subsequent hematochesia and a drop in Hgb/Hcrt. The invention provides a conservative treatment for diffused GI bleeding which works on extensive areas of the GI mucosa. The treatment (1) stops the chronic diffuse GI bleeding, (2) eliminates the need for further transfusions, with its attendant complications (3) treatment is as an outpatient without the need for surgery, (4) the patient is returned to an excellent quality of life, (5) there is a major saving to the health industry, and (6) there are no observed side effects.

REFERENCES:
patent: 5399551 (1995-03-01), Ise et al.
patent: 5554380 (1996-09-01), Cuca et al.
patent: 5670163 (1997-09-01), Cuca et al.
Erythropoietin and Anemia of Gastrointestinal Bleeding in a Jehovah's Witness, Jorge P. Ferrer et al.,Annals of Internal Medicine, vol. 112, No. 7, p. 552, Apr. 1990.
Search Result--1; Subject: Erythropoietin and Gastrointestinal Hemmorrhage, Jan. 13, 1998, pp. 1-5, Journal Article.

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