Treatment of central nervous disorders with imidazole compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514396, 514399, 514400, 514303, 514381, 514398, A61K 3141, A61K 31415, A61K 3144

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active

051791137

ABSTRACT:
Imidazole compounds such as 5-[4-(3-(N-isopropylamino)hydroxypropoxy)indole-2-carboxamidomethyl]-2-n-b utyl-1-[(2'-carboxybiphenyl-4-yl)methyl]-4-chloroimidazole and their pharmaceutically suitable salts are useful for treating central nervous system disorders, such as cognitive and learning disorders, mediated by angiotensin-II.

REFERENCES:
patent: 4301169 (1981-11-01), Yamanaka
patent: 4402996 (1983-09-01), Yamanaka et al.
patent: 4533669 (1985-08-01), Yamanaka et al.
patent: 4602031 (1986-07-01), Yamanaka et al.
patent: 4916129 (1990-04-01), Carini et al.
Mann, Exp. Brain Res., vol. 4, suppl. pp. 242, 1982.
Fitzsimons, Rev. Physiol. Biochem, Pharmacol., vol. 87, pp. 117, 1980.
Scholken et al., Experientia., vol. 38, pp. 469, 1982.
Koller, et al., Neuroscience Lett., vol. 14, pp. 71-75, 1975.
Morgan and Routtengerg, Science, vol. 196, pp. 87-89, 1977.
Arregui, et al., J. Neurochem, vol. 38, pp. 1490-1692, 1982.
Zubenko, et al., Biol. Psych., vol. 21, pp. 1365-1381, 1986.
Usinger, et al., Drug. Dev. Research, vol. 14, pp. 315-324, 1988.
Costall, et al., Pharmacol, Biochem. Behav., vol. 33, pp. 573-579, 1989.
Barnes, et al., Brain Research, vol. 491, pp. 136-143, 1989.
Chiu et al., Biochem and Biophys. Res. Comm., vol. 165, pp. 196-203, 1989.
Whitebread et al, Biochem and Biophys. Res. Comm., vol. 163, pp. 284-291.
Bennet and Snyder, J. Biol. Chem., vol. 254, pp. 7423-7430, 1976.
Unger et al., Circulation, vol. 77 (suppl. I), pp. 40-54 (1988).

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