Treatment of cell proliferative disorders using antibodies which

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Binds hormone or other secreted growth regulatory factor,...

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4241451, 53038824, 5303892, A61K 39395

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active

057831874

ABSTRACT:
Connective Tissue Growth Factor (CTGF) is a polypeptide growth factor for connective tissue cells. CTGF is related immunologically and biologically to PDGF, but is the product of a distinct gene. CTGF, nucleic acids encoding CTGF, means for producing CTGF, anti-CTGF antibodies, diagnostic and therapeutic methods for using CTGF, and methods for inhibition or stimulation of CTGF activity are disclosed.

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Ryseck, R.P. et al., Cell Growth and Differentiation 2:225-233, May 1991.

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