Treatment of cell culture microcarries

Textiles: fiber preparation

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C12B 300

Patent

active

040366936

ABSTRACT:
A method of treating certain cell culture microcarriers to improve their performance is disclosed. In this method, positively charged microcarriers, such as those produced by reacting polydextran beads with diethylaminoethyl, are treated by contacting them with macromolecular polyanions, such as carboxymethylcellulose, prior and/or during use in cultures. Such treatment overcomes deleterious effects previously observed in attempts to use these microcarriers in cell culture systems.

REFERENCES:
patent: 3850748 (1974-11-01), Cook et al.
patent: 3910819 (1975-10-01), Rembaum et al.

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