Treatment of body odor and disturbed keratinization

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Bacterium or component thereof or substance produced by said...

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424 65, 424 67, 424 68, 424294, 424295, 424319, A61K 31315

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active

040536300

ABSTRACT:
A treatment to prevent the symptoms of skin conditions characterized by an offensive odor of the body, and a treatment to alleviate the symptoms of diseases characterized by defects of keratinization consisting of the topical application of a solution, lotion, cream, ointment, powder, stick or spray containing cysteic acid, cysteinesulfinic acid, homocysteic acid or their metal chelates are disclosed. The metal chelates include molecular complexes of cysteic acid or its analogue and metal ions such as ferric, cupric, zinc and aluminum ions. The efficacious compositions may include the active ingredients present in a total amount of from 1 to 30 percent, and preferably from 2 to 10 percent by weight. In a prophylactic treatment topical application to skin areas of axilla, crotch (inguinalperineum) and feet has been found to prevent the formation of malodor. In a therapeutic treatment for the disturbed keratinization topical application to affected areas has been found to achieve a complete remission of ichthyosis, dandruff and acne.

REFERENCES:
johnston, Chemical Abstracts 78:80629k (1973).
Van Herreveld et al., Chemical Abstracts 76:2241x (1972).
McCully, Chemical Abstracts 75:73327v (1971).
Tsuchiya et al., Chemical Abstracts 73:23707g (1970).
Tanaka et al., Chemical Abstracts 70:68709p, (1969).
Zbigniew et al., Chemical Abstracts 68:48024s, (1968).

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