Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1985-06-17
1987-11-10
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
514885, A61K 3512
Patent
active
047056878
ABSTRACT:
Method of treating autoimmune diseases such as rheumatoid arthritis by administration of a suppressor factor obtained in the supernatant of a human cell line. A particular human cell line is CEM which has survived treatment with 6-thioguanine.
REFERENCES:
patent: 4239498 (1980-12-01), Rule
patent: 4364935 (1982-12-01), Kung et al.
"Graft-Versus-Host Disease in Murine Bone Marrow . . . ", Gorczynski et al., Immun. Ltrs. 11 (1985) 293-299.
"Purification and Characterization of a Suppressor Activating Factor", C. Lau et al., Abstracts, 6th Int'l Congress of Immun., Jul. 6-11, 1986, Toronto, Canada, No. 3.53.6.
"Suppressor-Activating Factor (SAF) Does Not Inhibit Interleukin 2 (IL 2) Receptor . . . ", Messino et al., Abstracts, 6th Int'l Congress of Immun., Jul. 6-11, 1986, Toronto, Canada, No. 6.13.21.
"Impaired Release of a T-cell Specific Suppressor Factor in Rheumatoid Arthritis", Lau et al., Clin. exp. Immunol. (1985) 61, 489-495.
"Treatment of Active Rheumatoid Arthritis with Slow . . . ", Malaise et al., The Lancet, Apr. 13, 1985, pp. 832-836.
"Effect of Thymopoietin Pentapeptide (TP5) on Autoimmunity", The Journal of Immunology, vol. 125, No. 4, Oct. 1980, pp. 1634-1638.
Nature, New Biology, "Induction of Red Cell Autoantibodies in Normal Mice", vol. 243, No. 128, Jun. 13, 1973, pp. 213-214.
Nature, "Suppressor T Cells in Experimental Autoimmune Haemolytic Anaemia", vol. 273, May 11, 1978, pp. 154-155.
Chem. Abst., 101:70779p, 1984.
Lau et al., J. Imm. 134(5):3155-3162, 1985.
Brown Johnnie R.
Ortho Pharmaceutical (Canada) Ltd.
Rollins Jr. John W.
LandOfFree
Treatment of autoimmune diseases such as rheumatoid arthritis wi does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of autoimmune diseases such as rheumatoid arthritis wi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of autoimmune diseases such as rheumatoid arthritis wi will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1067112