Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1996-10-04
1999-04-06
Criares, Theodore J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
552653, A61K 3159, C07J17500
Patent
active
058918655
ABSTRACT:
A method of treating arthritis symptoms induced by an infectious agent of an arthritis patient comprising administering to an arthritis patient an amount of vitamin D compound effective to reduce symptoms and observing a reduction in symptoms is disclosed.
REFERENCES:
patent: 4749710 (1988-06-01), Truitt et al.
patent: 4857518 (1989-08-01), DeLuca et al.
patent: 5098899 (1992-03-01), Gilbert et al.
M.M. Andre, et al., "Tenidap Inhibits T-cell Proliferation and Cytokine Production,." Sep. 1992, (Abstract).
A.K. Bhalla, et al., "1.25-Dihydroxyvitamin D.sub.3 inhibits Lymphocyte Proliferation and Interleukin 2 Production: A Potential New Immunosuppressant," 1985 (Abstract).
E. Borba, et al., "Lipoprotein (a) Level is Increased in Systemic Lupus Erythematosus," Sep. 1992 (Abstract).
M.T. Cantorna, et al., "1,25-Dihydroxyvitamin D.sub.3 Prevents and Ameliorates Symptoms in Two Experimental Models of Human Arthritis," Jan. 1997 (Abstract).
U.N. Das, "Interaction(s) Between Essential Fatty Acids, Eicosanoids, Cytokines, Growth Factors and Free Radicals: Relevance to New Therapeutic Strategies in Rheumatoid Arthritis and Other Collagen Vascular Diseases," Prostaglandins, Leukotrienes and Essential Fatty Acids 44 (4):201-210, 1991.
R.M. Flipo, et al., "Natural course of eroise arthropathy of the hands in dialized patients," Sep. 1992 (Abstract).
P. Goupille and J. -P. Valat, "Le Traitement du rhumatisme psoriasique," Ann. Med. Interne. 145 (3) :205-214, 1994.
R.A. Greenwald, et al., "Metalloproteinase (MMP) Activity and Radiologic Severity of Adjuvant Arthritis (AA) : Synergistic Beneficial Effects of Tenidap 9TD) and 4-dedimethylaminotetracycline (CMT) ," Sep. 1992 (Abstract).
M.E. Hayes, et al., "Synthesis of the active metabolite of vitamin D, 1,25 (OH).sub.2 D.sub.3, by synovial fluid macrophages in arthritic diseases," Ann. Rheum. Dis. 48 : 723-729, 1989.
M.F. Holick, "Noncalcemic Actions of 1,25-Dihydroxyvitamin D.sub.3 and Clinical Applications," Bone 17 (2):107S-111S, 1995.
D. Huckins, et al., "Treatment of Psoriatic Arthritis with Oral 1,25-Dihydroxyvitamin D.sub.3 : A Pilot Study," Arth. Rheum. 33 (11) :1723-1727, 1990.
J. Martel-Pelletier, et al., "Tenidap, a New Anti-rheumatic Drug, Reduced IL-1R Expression and IL-1-induced Expression of Metalloproteases in Cartilage Human Chondrocytes," Sep. 1992 (Abstract).
K. Muller and K. Bendtzen, Inhibition of Human T Lymphocyte Proliferation and Cytokine Production by 1,25-Dihydroxivitamin D.sub.3. Differential Effects on CD45RA+ and CD45RO+ Cells, Autoimmunity 14:37-43, 1992.
M.H. Pioro and J.M. Cash, "Treatment of Refractory Psoriatic Arthritis," Rheumatic Disease Clinics of North America 21 (1) :129-149, 1995.
A. Raj, et al., "Evidence for Local Synthesis of 1,25-dihydroxyvitamin D in the Synovial Compartment of the Joint in Pitentis with Inflammatory Arthritis," Sep. 1992 (Abstract).
F. Shapiro, "Osteopetrosis,"Clin. Ortho. Rel. Res. 294 : 34-44, 1993.
S. Yang, et al., "1.alpha.25-dihydroxyvitamin D.sub.3 and 19-nor-1.alpha.,25-dihydroxyvitamin D.sub.2 suppress immunoglobulin production and thymic lymphocyte proliferation in vivo," Biochemica et Biophysica Acta 1158: 279-286, 1993.
Cantorna Margherita T.
DeLuca Hector F.
Hayes Colleen E.
Criares Theodore J.
Wisconsin Alumni Research Foundation
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