Treatment of an extracorporeal stream of blood with a dialyzable

Details Treatment of an extracorporeal stream of blood with a dialyzable Treatment of an extracorporeal stream of blood with a dialyzable

1979-06-14

1982-05-18

Fagelson, Anna P.

Surgery

Respiratory method or device

Ozone or ion generation

23230B, 128214B, 128653, 128654, 128655, 128659, 128760, 210645, 210646, 210647, 210648, 210651, 2103213, 210927, 250302, 250304, 424 1, 424 7, 424 8, 424 9, 424101, 424129, A61K 3300, A61M 500, G01N 3100, G01N 3348, G01N 3352, G01N 3384, G01N 3500, A61K 4900

Patent

active

043299865

ABSTRACT:
A therapeutic composition suitable for extracorporeal treatment of whole blood comprises a dialyzable chemotherapeutic agent and a dialyzable fluorescable tracer means. The removal rate of the fluorescable tracer compound from treated blood during hemodialysis is a function of the removal rate of unreacted chemotherapeutic agent present. The residual chemotherapeutic agent concentration after hemodialysis is ascertained by measuring the concentration of the fluorescable tracer compound in a dialysate using fluorometric techniques.

REFERENCES:
patent: B409220 (1975-01-01), Stein
patent: 2650709 (1953-09-01), Rosenak
patent: 3459176 (1969-08-01), Leonard
patent: 3483867 (1969-12-01), Markovitz
patent: 3719182 (1973-03-01), Rose
patent: 3785772 (1974-01-01), Coggeshall
patent: 3814939 (1974-06-01), Parker
patent: 3833724 (1974-09-01), Cerami
patent: 4081372 (1978-03-01), Atkin
patent: 4123353 (1978-10-01), Hakansson
Babb, Carbamylated Red Cell Distributions in Blood Treated Extracorporeally with Cyanate, Final Report Prepared for Div. of Blood & Dis. Resources Nat. Heart, Lung & Blood Inst., Bethesda, Md., Contract No. 1-HB-6-2962, U.S. NTIS PB Rep. 1977-PB274862, Jul. 1977.
Rabb, Chem. Abs., vol. 89, 1978, Ab. No. 613.

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