Treatment of aluimmunization and refractoriness to platelet tran

Details Treatment of aluimmunization and refractoriness to platelet tran Treatment of aluimmunization and refractoriness to platelet tran

1991-11-15

1994-01-11

Isabella, David

Surgery

Blood drawn and replaced or treated and returned to body

A61M 3700

Patent

active

052777014

ABSTRACT:
The invention provides a therapeutic method for treating refractoriness to platelet transfusion by isolating blood serum from an alloimmunized patient undergoing platelet transfusion therapy, passing the serum through a bed comprising staphococcal protein A coupled to a solid support and returning the treated plasma to the patient. The method can be conducted by batch-type procedure or by continuously conducting the steps so that blood is withdrawn, passed through the bed, and returned to the patient as a continuous stream. The method is useful to treat alloimmunized patients suffering from leukemia, aplastic anemia, myelofibrosis, myelodysplastic syndrome, or in a bone marrow transplant patient.

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