Treatment of allergy

Details Treatment of allergy Treatment of allergy

1984-09-17

1988-04-26

Kight, John

Drug, bio-affecting and body treating compositions

Lymphokine

424 88, 424 91, 530389, 530390, 530391, 514826, 514829, 514890, A61K 39395, A61K 3935

Patent

active

047403713

ABSTRACT:
In the treatment of allergy, desensitization is effected by administering the allergen in admixture with an antibody thereto, the antibody being present in a molar excess. The antibody is preferably one raised in the patient.

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Caulfield et al, "Induction of Idiotype-Specific Suppressor T Cell with Antigen/Antibody Complexes", 157, J. Exp. Med., 1713 (1983).
Blaser et al, "Immune Networks in Immediate Type Allergic Diseases", 418, Ann. NY Acad. Sci., 330 (1983).
Blaser et al, "Regulation of the IgE Antibody Response by Idiotype-Anti-Idiotype Network", 32, Prog. Allergy, 203 (1982).
Blaser et al, "Regulatory Effects of Isologous Anti-Idiotypic Antibodies on the Formation of . . . ", 14, Eur. J. Immunol., 93-98 (1984), 50, Fed. Reg., 3082 (Jan. 23, 1985).

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