Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1995-05-26
1998-05-12
Azpuru, Carolos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 45, 424434, 424435, 424449, 424451, 424464, 514185, 514815, 540145, A61F 202, A61L 904, A61K 970, A61K 31555
Patent
active
057501327
ABSTRACT:
The present invention relates to methods of lessening the severity and frequency of adverse effects associated with administration of extracellular hemoglobin comprising administration of a smooth muscle relaxant. Preferred smooth muscle relaxants are terbutaline and nifedipine, which can be administered in a prophylactic treatment, responsive regimented treatment or responsive intermittent treatment.
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Physicians Desk Reference (1993), Published by Medical Economics Data, Montvale, NJ/Terbutaline-PG 1057, 1060, 1059, 1364, 1365/Nifedipine-PG 1631, 1838, 1840, 1852, 1850/Nicardipine-PG 2393, 2395/Nitroglycerine-PG 958, 1191, 1353, 1387, 1388, 1800,1801, 1920, 2160, 2237, 2268, 2386/Atropine-PG 557, 608, 625, 719, 859, 1940, 1941, 2510, 2264/Na-Nitroprusside-PG 1999/Diphenhydramine-PG 1416, 1420, 1745, 1746, 1829/Cimetidine-PG 2321, /Methylpredinsolone-PG 2246, 2478,/Hydrocortisone-PG 1532,2476,/Glycogen-PG 1297,/Naloxone-PG 952, 2169.
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Azpuru Carolos A.
Brown Theresa A.
Novelli Marianne F.
Somatogen, Inc.
Stewart Ramsey R.
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