Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1981-08-27
1983-09-20
Rosen, Sam
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424319, 424 10, A61K 3122
Patent
active
044056435
ABSTRACT:
Pharmaceutical compositions for use in the relief of acute pulmonary edema, different types of shock including anaphylactic shock, shock induced by bacterial endotoxins, and hyperfibrinolysis induced by substances which activate plasminogen, consist of solutions of an ester of L-arginine with an aliphatic alcohol in water at a pH between 5.5 and 8.5. The compositions may be provided in unit dosage form containing 0.25-100 mg of active substance per kilogram of body weight of the subject in need of treatment and are administered through the parenteral route. The esters may be provided in the form of a salt with a pharmaceutically acceptable organic or inorganic acid. The esters may be with methyl or ethyl alcohol. The compositions are more effective than aspirin and aprotinin.
REFERENCES:
The Pharmacological Basis of Therapeutics 6th ed. MacMillan Pub. Co., NY Goodman et al., p. 870, 1980.
Baglioni Alessandro
Sportoletti Giancarlo
Italfarmaco S.p.A.
Rollins, Jr. John
Rosen Sam
LandOfFree
Treatment of acute pulmonary edema with arginine esters does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of acute pulmonary edema with arginine esters, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of acute pulmonary edema with arginine esters will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-588124