Drug – bio-affecting and body treating compositions – Lymphokine – Interleukin
Patent
1991-05-16
1994-07-05
Draper, Garnette D.
Drug, bio-affecting and body treating compositions
Lymphokine
Interleukin
435 695, 435 6952, 435 697, 435 7021, 514824, 514 2, 514 8, 514 21, 935106, 935107, 935109, 4241831, 4241441, A61K 3702
Patent
active
053265599
ABSTRACT:
The invention features a method for treating a patient suffering from accelerated atherosclerosis in a patient suffering from vascular damage, e.g., damage caused by percutaneous transluminal coronary angioplasty (PTCA), heart transplantation, or coronary vein graft. The method includes administering to the patient a molecule which is capable of specifically binding to a interleukin receptor expressed on a cell of the patient which contributes to the process of accelerated atherosclerosis. The molecule is capable of decreasing the viability of the cells.
REFERENCES:
Clowes et al. Nature 265:625, 1977.
Hoover et al., Cir. Res. 47:578, 1980.
Guyton et al., Cir. Res. 46:625, 1980.
Cunningham et al., Radiology 151:487, 1984.
Shore et al., Cellular Immunol. 100:210, 1986.
Hanson et al., J. Clin. Invest. 81:149, 1988.
Kelley et al., Proc. Nat'l. Acad. Sci, USA 85:3980, 1988.
Schwartz et al., N. Engl. J. Med. 318:1714, 1988.
Heras et al., Circulation 79:657, 1989.
IP et al., J. Am. College Cardiol. 5:1667, 1990.
Lorberboum-Gaski et al., J. Biol. Chem. 265:16311, 1990.
Sarenbock et al., Circulation 82:111-208, 1990.
Muller et al., Circulation 82:111-429, 1990.
Murphy et al., Circulation 82:111-429, 1990.
Casscells et al., Circulation 82:111-208, 1990.
Bastos et al, J. Immunol. 145, 1990, pp. 3535-3539.
LandOfFree
Treatment of accelerated atheosclerosis with interleukin-2 recep does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treatment of accelerated atheosclerosis with interleukin-2 recep, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treatment of accelerated atheosclerosis with interleukin-2 recep will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-794924