Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...
Patent
1990-07-11
1991-11-26
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Radical -xh acid, or anhydride, acid halide or salt thereof...
A61K 31185
Patent
active
050682539
ABSTRACT:
The present invention relates to a method of treating or preventing a microbial infection, such as Pneumocystis carinii or Toxoplasma gondii, in a patient comprising administering to the patient an antimicrobially effective amount of p-acetamidobenzoic acid or a pharmaceutically acceptable salt thereof so that the microbial infection is inhibited. P-acetamidobenzoic acid or an acceptable salt thereof can be used to treat infections caused by Pneumocystis carinii, Toxoplasma gondii, Plasmodium species and other microorganisms containing the enzyme dihydropteroate synthetase such as most bacteria and some yeasts. The method of the present invention is particularly applicable in situations where the patient is immunosuppressed.
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patent: 4835177 (1989-05-01), Durette
patent: 4866035 (1989-09-01), Durette
patent: 4866036 (1989-09-01), Durette
patent: 4868155 (1989-09-01), Durette et al.
patent: 4868157 (1989-09-01), Durette
Pedersen et al., "The Efficacy of Inosine Pranobex in Preventing the Acquired Immunodeficiency Syndrome in Patients with Human Immunodeficiency Virus Infection", The New England Journal of Medicine, vol. 322, Jun. 21, 1990, vol. 322, No. 25, pp. 1757-1809.
Allegra Carmen
Kovacs Joseph
Masur Henry
Friedman Stanley J.
The United States of America as represented by the Department of
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