Treatment for necrotizing infections

Details Treatment for necrotizing infections Treatment for necrotizing infections

1998-12-11

2000-11-07

Weddington, Kevin E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514199, 514200, 514252, 514255, 514311, 514474, 514494, A61K 31535, A61K 3143, A61K 31545, A61K 31495, A61K 31445

Patent

active

061437425

ABSTRACT:
The treatment of for arresting the destructive effects of proteolytic enzymes produced by a host infecting organism, such as "flesh eating bacteria", is carried out using therapy with includes the administration of one or more protease inhibitors.

REFERENCES:
patent: 5196438 (1993-03-01), Martin et al.
patent: 5413999 (1995-05-01), Vacca et al.
Holder, Ian Alan, "Experimental studies of the pathogenesis of infections due to Pseudomonas aeruginosa: effect of treatment with protease inhibitors", Rev. Infect. Dis., 5(Suppl. 5) p. 914-921 (abstr).
Meltzer et al., "Necrotizing Fasciitis: A diagnostic Challenge", American Family Physician, Jul. 1997, pp145-149.
Amy Pakyz and Debra Israel, "Overview of Protease Inhibitors", Journal of the American Pharmaceutical Association, vol. NS37, No. 5, Sep./Oct. 1997, pp 543-551.

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