Treatment for itch of chicken pox

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424450, 424 9421, 424 9645, 424405, 514886, 514887, 514862, 514873, A61K 748

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active

056701420

ABSTRACT:
A method for reducing the itch and the scarring associated with chicken pox is disclosed. The method entails applying a topical pharmaceutical formulation of papain, pancreatin or subtilisin to the skin proximate to the vesicles. To further reduce scarring, an antibiotic is applied with the papain, pancreatin or subtilisin. Compositions are provided in the form of solutions, lotions, ointments and salves containing papain, pancreatin or subtilisin and, optionally, a surfactant, an antibiotic and a penetration enhancer.

REFERENCES:
patent: 4166108 (1979-08-01), Brown
patent: 4331653 (1982-05-01), Brown
patent: 5441740 (1995-08-01), Ozien
patent: 5444096 (1995-08-01), MccreA
patent: 5476853 (1995-12-01), Cauwenbergh
patent: 5543149 (1996-08-01), Rubin
Hagermark, Osten; Influence of Antihistamines, Sedatives, and Aspirin on Experimental Itch; Acta Derm. Venerol. (1973), 53(5) pp 363-368 Dec. 3, 1973.
Davies et al.; The efficacy of Histamine Antagonists as Antipruritics in Experimentally Induce Pruritis; Archives of Dermatogolog Research (1979), 266(2), 117-20 Dec. 1, 1979.

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