Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – 9,10-seco- cyclopentanohydrophenanthrene ring system doai
Patent
1990-03-29
1991-11-05
Waddell, Frederick E.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
9,10-seco- cyclopentanohydrophenanthrene ring system doai
552653, A01N 4500, C07J17200, C07J17500
Patent
active
050632213
ABSTRACT:
A treatment for hyperparathyroidism with use of a 1.alpha.-hydroxyvitamin D derivative of the formula (I) ##STR1## wherein R is a branched alkyl group having 4-6 carbon atoms that is substituted by one or two hydroxyl groups or a cyclopropylhydroxymethyl group, are disclosed. A pharmaceutical composition comprising the above derivatives is useful as a therapeutic agent for hyperparathyroidism such as secondary hyperparathyroidism.
REFERENCES:
patent: 4230701 (1980-10-01), Holick et al.
patent: 4812304 (1989-03-01), Anderson et al.
patent: 4948789 (1990-08-01), Slatopolsky
Nishii Yasuho
Takita Yumiko
Chugai Seiyaku Kabushiki Kaisha
Criares T. J.
Waddell Frederick E.
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