Treatment for diseases involving inflammation

Details Treatment for diseases involving inflammation Treatment for diseases involving inflammation

1995-01-31

1997-10-07

Achutamurthy, Ponnathapura

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

424 851, 514 2, 514 21, 514826, 514851, A61K 3820, A61K 4505

Patent

active

056744838

ABSTRACT:
The present invention relates to a method to protect an animal from a disease involving inflammation by treating that animal with an effective amount of IL-12. The present invention also relates to a method for prescribing treatment for a respiratory disease involving an inflammatory response and a method for monitoring the success of a treatment for a respiratory disease involving an inflammatory response in an animal. Also included in the present invention is a formulation comprising IL-12 and a compound capable of enhancing the effectiveness of the IL-12 at protecting an animal from a disease involving inflammation.

REFERENCES:
patent: 4944941 (1990-07-01), Amman
patent: 5300292 (1994-04-01), Ulich
patent: 5368854 (1994-11-01), Rennick
Afonso et al., 1994, Science, 263:235-236.
Heinzel et al., 1993, J. Exp. Med., 177:1505-1509.
Hsieh et al., 1993, Science, 260:547-549.
Sypek et al., 1993, J. Exp. Med., 177:1797-1802.

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