Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-10-17
1999-03-02
Lambkin, Deborah C.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514599, 514712, 514707, 514330, 514212, 514551, A61K 3140, A61K 3116, A61K 3110, A61K 3155
Patent
active
058772030
ABSTRACT:
Dithiocarboxylates, and in particular, dithiocarbamates, block the induced expression of the endothelial cell surface adhesion molecule VCAM-1, and are therefor useful in the treatment of cardiovascular disease, including atherosclerosis, post-angioplasty restenosis, coronary artery diseases, and angina, as well as noncardiovascular inflammatory diseases that are mediated by VCAM-1.
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Alexander R. Wayne
Medford Russell M.
Offermann Margaret K.
Emory University
Haley Jacqueline
Knowles Sherry M.
Lambkin Deborah C.
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