Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-06-07
1998-08-11
O'Sullivan, Peter
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514210, 514315, 514478, 514479, 514484, 514485, 514487, 514488, 514489, 514506, 514513, 514824, 514825, 514826, 514861, 514863, 546245, 548531, 548953, 558230, 558235, 564 76, 568 21, 568 25, A61K 31445, A61K 3140, A61K 31395
Patent
active
057927871
ABSTRACT:
Dithiocarboxylates, and in particular, dithiocarbamates, block the induced expression of the endothelial cell surface adhesion molecule VCAM-1, and are therefor useful in the treatment of cardiovascular disease, including atherosclerosis, post-angioplasty restenosis, coronary artery diseases, and angina, as well as noncardiovascular inflammatory diseases that are mediated by VCAM-1.
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Alexander R. Wayne
Medford Russell M.
Offermann Margaret K.
Emory University
Haley Jacqueline
Knowles Sherry M.
O'Sullivan Peter
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