Treatment and control of dry eye by use of biodegradable...

Details Treatment and control of dry eye by use of biodegradable... Treatment and control of dry eye by use of biodegradable...

2007-04-17

2007-04-17

Woodward, Michael P. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S400000, C424S422000, C424S426000, C128S202250, C128S202250

Reexamination Certificate

active

10355772

ABSTRACT:
A treatment for dry eye and other eye problems using a plug system or a delivery system. The plug system comprises solid, porous or hollow microcapsules composed of a biodegradable biocompatible polymer. The capsules are stored in the form of a powder that can be suspended in an aqueous carrier solution or dispersed in a gel or an ointment. Alternatively a biodegradable biocompatible capsule having a treating agent encapsulated within a polymer shell or a polymer sphere, again stored in the form of a powder that can be suspended in an aqueous carrier solution or dispersed in a gel or an ointment. The plug system prevents excretion of the capsules and their size is larger then the punctum and to prevent entrance to the lachrymal excretory system. The treatment is slowly released into the eye through the polymer shell or sphere and/or gets secreted as the polymer degrades.

REFERENCES:
patent: 3867519 (1975-02-01), Michaels
patent: 3981303 (1976-09-01), Higuchi et al.
patent: 3986510 (1976-10-01), Higuchi et al.
patent: 3993071 (1976-11-01), Higuchi et al.
Merck and Co. Disclosure, “Lacrisert” 1998.

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