Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Nitrates or nitrites or nitric acid or nitrogen oxides
Reexamination Certificate
2006-05-16
2006-05-16
Pak, John (Department: 1616)
Drug, bio-affecting and body treating compositions
Inorganic active ingredient containing
Nitrates or nitrites or nitric acid or nitrogen oxides
C424S600000, C424S607000, C424S703000, C424S708000, C424S709000, C424S711000, C424S713000, C514S474000, C514S561000, C514S562000, C514S563000, C514S645000, C514S663000, C514S708000, C514S709000, C514S711000, C514S740000, C514S771000, C514S826000, C514S851000, C514S929000, C514S958000, C514S959000
Reexamination Certificate
active
07045152
ABSTRACT:
Pulmonary disorders in which the GSNO pool or glutathione pool in the lung is depleted and where reactive oxygen species in lung are increased, are treated by delivering into the lung as a gas, agent causing repletion or increase of the GSNO pool or protection against toxicity and does so independently of reaction with oxygen. Agents include ethyl nitrite, NOCl, NOBr, NOF, NOCN, N2O3, HNO, and H2S. Optionally, N-acetylcysteine, ascorbate, H2S or HNO is administered in addition to other GSNO repleting agent to potentiate the effect of said agent.
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Duke University
Elrifi Ivor R.
Mintz Levin Cohn Ferris Glovsky and Popeo P.C.
Pak John
Pavao Matthew
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