Treating central nervous system diseases

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

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514178, 514182, 514879, A61K 3156

Patent

active

049026801

ABSTRACT:
A method of treating humans suffering from central nervous system diseases, such as Alzheimer's disease, Parkinsons's disease, senile dementia. The treatment consists of inducing into the patient's blood stream at least one from the group consisting of: sex hormones and anabolic hormones. Growth hormone is also be used in those patients in advanced stages of the disease, or in those patients where it has been determined that a low level of growth hormone is present. A method of diagnosing Alzheimer's disease, senile dementia, by the determination of the levels of the hormones somatotropin (human growth hormone) and somatomedin-C (IGF-I) after the administration of the Aroonsakul-Allen provocative test is also disclosed. Blood-sera samples are taken at certain time periods after the administration of L-Dopa, and the samples are tested for the levels of these hormones. These levels are then compared against the levels for normal subjects.

REFERENCES:
patent: 3274060 (1966-09-01), Bossinger
patent: 4746674 (1988-05-01), Pierpaoli et al.
Cotzias et al., CA 86: 50823s (1977).
Hugino, CA 95: 3943y (1981).
Fillit et al., Biosis 83: 58220 (1986).

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