Treating an arteriosclerosis with glimepiride

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514824, A61K 31095, A61K 3140

Patent

active

054161053

ABSTRACT:
A pharmaceutical composition containing as an active ingredient glimepiride. The composition is used for preventing or treating arteriosclerosis with no influence on lipid metabolism and no increase in plasma insulin level.

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Y. Ozaki et al., "Effects of Oral Hypoglycaemic Agents on Platelet Functions", Biochemical Pharmacology, vol. 44, No. 4, pp. 687-691, 1992.
M. Omosu et al., "Effects of Hoe 490, A New Oral Antidiabetic Agent, on Platelet Aggregation", Japan J. Pharmacol., vol. 49, p. 328P, 1989.
Z. Aranyi, "Clinical and Experimental Comparison of the Cardiovascular Effects of Glibenclamide, Glimepiride and Gliclazide in Diabetes", vol. 24, Supplement I, p. S228, 1992.
G. Marquie, "Effects Preventifs du Gliclazide sur le Developpement de l'atherosclerose induite par le cholesterol chez le Lapin", C. R. Acad. Sc. Paris, Serie D, vol. 285, pp. 197-200, Jul. 11, 1977.

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