Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Heart valve – Having rigid or semirigid pivoting occluder
Patent
1991-03-05
1993-03-09
Isabella, David
Prosthesis (i.e., artificial body members), parts thereof, or ai
Heart valve
Having rigid or semirigid pivoting occluder
623 11, 623 66, 427 2, A61F 224, A61F 202, A61F 254, A01N 102
Patent
active
051923122
ABSTRACT:
Tissue which is suitable for transplant is treated with a growth factor and cells which populate the tissue and native cells must be removed, they cannot be "masked" reduce immunogenicity; this increases the longevity of the tissue upon transplant. The preferred growth factor is basic fibroblast growth factor, and the preferred cells are fibroblasts. The tissue can be an allograft or xenograft taken from a cow, pig or other mammal.
REFERENCES:
patent: 4407787 (1983-10-01), Stemberger
patent: 4485096 (1984-11-01), Bell
patent: 4539716 (1985-09-01), Bell
patent: 4546500 (1985-10-01), Bell
patent: 4609551 (1986-09-01), Caplan
patent: 4642120 (1987-02-01), Nevo et al.
patent: 4785079 (1988-11-01), Gospodarowicz
patent: 4828563 (1989-05-01), Muller-Lierheim
patent: 4835102 (1989-05-01), Bell et al.
patent: 4870160 (1989-09-01), Charonis et al.
patent: 4878913 (1989-11-01), Aebischer et al.
patent: 4890457 (1990-01-01), McNally et al.
patent: 4902782 (1990-02-01), Gospodarowicz
patent: 4950483 (1990-08-01), Ksander et al.
patent: 4960424 (1990-10-01), Grooters
patent: 4973493 (1990-11-01), Guire
O'Brien, et al., A Comparison of Aortic Valve Replacement with Viable Cryopreserved and Fresh Allograft Valves, with a Note on Chromosomal Studies, J. Thoracic & Cardiovascular Surg. 94:812-823 (1987).
Slavkin, et al., Concepts of Epithelial-Mesenchymal Interactions During Development: Tooth and Lung Organogenesis, J. Cellular Bioch. 26:117-125 (1984).
Manu-Tawiah and Martin, Peat Extract as a Carbon Source for the Growth of Pleurotus ostreatus Mycelium, J. Sci. Food Agric. 47:243-247 (1989).
Nichols, et al., Cytogenetic Evaluation of Human Endothelial Cell Cultures, C. Cellular Phys. 132:453-462 (1987).
Nanchahal, et al., Cultured Composite Skin Grafts: Biological Skin Equivalents Permitting Massive Expansion, The Lancet 2 (1989) 22:191-193 (Jul. 22, 1989).
Shiogama, et al., An Improved Cryopreservation Procedure for Human Fetal Pancreas Tissues, Biological Abstracts, vol. 85, Abstract No. 46563 (1988).
Shingh, et al., Binding of Tumor-Derived Angiogenic Factor to High Affinity Receptor on Endothelial Cells, J. Cell Biology 103:299a, Abstract No. 1107 (1986).
Bell, et al., Living Tissue Formed in vitro and Accepted as Skin-Equivalent Tissue of Full Thickness, Science 211:1052-1054 (1981).
Weinberg and Bell, A Blood Vessel Model Constructed from Collagen and Cultured Vascular Cells, Science 231:397-400 (1986).
Kent, et al., Species Variation and the Success of Endothelial Seeding, J. Vascular Surg. 9:271-276 (1989).
Hoch et al., In vitro Endothelialization of an Aldehyde-Stabilized Native Vessel, J. Surg. Res. 44:545-554 (1988).
Noyes, Culture of Human Fetal Liver, Proc. Soc. Exp. Biol. Med. 144:245-248 (1973).
Leapman, et al., Transplantation of Fetal Intestine: Survival and Function in a Subcutaneous Location in Adult Animals, Ann. Surg. 179:109-114 (1974).
Brockbank, Repopulation of Xenograft Heart Valves with Fibroblasts, Small Business Innovation Research Grant Application No. PHS 90-2 (Submitted Aug. 15, 1990).
Colorado State University Research Foundation
Isabella David
Nguyen Dinh X.
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