Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Heart valve – Having rigid or semirigid pivoting occluder
Patent
1995-06-05
1999-05-04
Clarke, Robert A.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Heart valve
Having rigid or semirigid pivoting occluder
435371, A61F 224
Patent
active
058999361
ABSTRACT:
This disclosure includes a method for generating a functional hybrid bioprosthesis. Tissue formed naturally of interstitial collagens is treated to kill native cells and remove potentially immunologically active soluble molecules. Then it may be treated sequentially with extracellular matrix adhesion factor, extracellular matrix glycosaminoglycan, and growth factor appropriate to the cell type required to function within the matrix, and incubating the transplant tissue matrix with cells that are either allogeneic or autologous for the recipient thereby imparting to the matrix the characteristics of the cell type and tissue selected. Tissues with a variety of functional bioactivities can thus be formed in vitro prior to graft transplantation or implantation which will exhibit reduced or no stimulation of an immunological response in the recipient.
REFERENCES:
patent: 3966401 (1976-06-01), Hancock et al.
patent: 4240794 (1980-12-01), Holman et al.
patent: 4323358 (1982-04-01), Lentz et al.
patent: 4378224 (1983-03-01), Nimni et al.
patent: 4383832 (1983-05-01), Fraefel et al.
patent: 4402697 (1983-09-01), Pollock et al.
patent: 4405327 (1983-09-01), Pollock
patent: 4407787 (1983-10-01), Stemberger
patent: 4485096 (1984-11-01), Bell
patent: 4539716 (1985-09-01), Bell
patent: 4546500 (1985-10-01), Bell
patent: 4553974 (1985-11-01), Dewanjee
patent: 4559298 (1985-12-01), Fahy
patent: 4567847 (1986-02-01), Linner
patent: 4609551 (1986-09-01), Caplan
patent: 4642120 (1987-02-01), Nevo et al.
patent: 4647283 (1987-03-01), Carpentier et al.
patent: 4648881 (1987-03-01), Carpentier et al.
patent: 4688387 (1987-08-01), Conaway
patent: 4707998 (1987-11-01), Linner et al.
patent: 4776853 (1988-10-01), Klement et al.
patent: 4785079 (1988-11-01), Gospodarowicz
patent: 4798611 (1989-01-01), Freeman, Jr.
patent: 4799361 (1989-01-01), Linner
patent: 4801299 (1989-01-01), Brendel et al.
patent: 4828563 (1989-05-01), Muller-Lierheim
patent: 4835102 (1989-05-01), Bell et al.
patent: 4838888 (1989-06-01), Nashef
patent: 4865871 (1989-09-01), Livesey et al.
patent: 4870160 (1989-09-01), Charonis et al.
patent: 4878913 (1989-11-01), Aebischer et al.
patent: 4890457 (1990-01-01), McNally et al.
patent: 4902782 (1990-02-01), Gospodarowicz
patent: 4911710 (1990-03-01), Milthorpe et al.
patent: 4960424 (1990-10-01), Grooters
patent: 4964280 (1990-10-01), Piunno et al.
patent: 4973493 (1990-11-01), Guire
patent: 5002566 (1991-03-01), Carpentier et al.
patent: 5131850 (1992-07-01), Brockbank
patent: 5145770 (1992-09-01), Tubo et al.
patent: 5192312 (1993-03-01), Orton
patent: 5197985 (1993-03-01), Caplan et al.
patent: 5215541 (1993-06-01), Nashef et al.
patent: 5336616 (1994-08-01), Livesey et al.
O'Brien, et al. A Comparison of Aortic Valve Replacement with Viable Cryopreserved and Fresh Allograft Valves, with a Note on Chromosomal Studies, J. Thoracic & Cardiovascular Surg. 94:812-823 (1987).
Slavkin, et al., Concepts of Epithelial-Mesenchymal Interactions During Development: Tooth and Lung Organogenesis, J. Cellular Bioch. 26:117-125 (1984).
Manu-Tawiah and Martin, Peat Extract as a Carbon Source for the Growth of Pleurotus ostreatus Mycelium, J. Sci. Food Agric. 47:243-247 (1989).
Nichols, et al., Cytogenetic Evaluation of Human Endothelial Cell Cultures, C. Cellular Phys. 132:453-462 (1987).
Nanchahal, et al., Cultured Composite Skin Grafts: Biological Skin Equivalents Permitting Massive Expansion, The Lancet 2 (1989) 22:191-193 (Jul. 22, 1989).
Shiogama, et al., An Improved Cryopreservation Procedure for Human Fetal Pancreas Tissues, Biological Abstracts, vol. 85, Abstract No. 46563 (1988).
Shingh, et al., Binding of Tumor-Derived Angiogenic Factor to High Affinity Receptor on Endothelial Cells, J. Cell Biology 103:299a, Abstract No. 1107 (1986).
Bell, et al., Living Tissue Formed in vitro and Accepted as Skin-Equivalent Tissue of Full Thickness, Science 211:1052-1054 (1981).
Weinberg and Bell, A Blood Vessel Model Constructed from Collagen and Cultured Vascular Cells, Science 231:397-400 (1986).
Kent, et al., Species Variation and the Success of Endothelial Seeding, J. Vascular Surg. 9:271-276 (1989).
Hoch, et al., In Vitro Endothelialization of an Aldehyde-Stabilized Native Vessel, J. Surg. Res. 44:545-554 (1988).
Noyes, Culture of Human Fetal Liver, Proc. Soc. Exp. Biol. Med. 144:245-248 (1973).
Leapman, et al., Transplantation of Fetal Intestine: Survival and Function in a Subcutaneous Location in Adult Animals, Ann. Surg. 179:109-114 (1974).
Brockbank, Repopulation of Xenograft Heart Valves with Fibroblasts, Small Business Innovation Research Grant Application No. PHS 90-2 (submitted Aug. 15, 1990).
Ninnemann, et al., Clinical Skin Banking: A Simplified System for Processing, Storage, and Retrieval of Human Allografts, Third Denver Postgraduate Institute in Emergency Medicine, Denver General Hospital, Denver, Colorado, 723-725, (held Oct. 23-28, 1978).
Abbott, et al., Absence of Antigenicity in Freeze-Dried Skin Allografts, Cryobiology, vol. 6, No. 5, 416-418 (1970).
Barlyn, et al., Frozen Skin Autografts Protected by Dimethyl Sulfoxide, Surgical Forum on Plastic Surgery, vol. XV, 475-477 (Oct. 1964).
Berggren, et al., Clinical Use of Viable Frozen Human Skin, JAMA vol. 194, No. 2, 129-131 (Oct. 1965).
Bondoc, et al., Clinical Experience with Viable Frozen Human Skin and a Frozen Skin Bank, Presented at Annual Meeting of American Surgical Association, Boca Raton, Florida (Mar. 24-26, 1971).
Brown, et al., Laboratory Investigations of Skin Viability Following Preservation by Various Methods, Surgial Forum on Plastic Surgery, vol VI, 577-581 (Nov. 1995).
Chambler, et al., The Use of Etox Lyophilised Skin in Burns, Journal Plastic Surgery 22(3) 210-215 (Jul. 1969).
Chalmers, Transplantation Immunity in Bone Homografting, Journal of Bone and Joint Surgery, vol. 41B, No. 1, 160-179 (Feb. 1959).
Cinamon, et al., A Simplified Testing System to Evaluate Performance After Transplantation of Human Skin Preserved in Glycerol or in Liquid Nitrogen, Journal of Burn Care & Rehabilitation, 435-439, (Jul./Aug. 1993).
Cochrane, et al., The Low Temperature Storage of Skin: A Preliminary Report, Journal Plastic Surgery, vol. 21 (1968).
Cram, et al., Short-term Preservation of Human Autografts, presented at Annual Meeting of American Burn Association, New Orleans, LA (Mar. 1983).
De Loecker, et al., Metabolic Changes in Human Skin Preserved at -3 and at -196C, Cryobiology 17, 46-53 (1980).
De Loecker, et al., Metabolic Changes in Rat Skin during Preservation and Storage in Glycerol Buffer at -196C, Cryobiology 12, 24-30 (1976).
Dogo, Treatment of Extensively Burned Patients with Freeze-Dried Homologous Skin (a long term appraisal of the results), ACTA Chirgugiae Plasticae, 187-198 (1965).
Friedlaender, et al., Studies on the Antigenicity of Bone, Journal Bone Joint Surgery (AM), 851-858 (Sep. 1976).
Georgiade et al., A Clinical and Experimental Investigation of the Preservation of Skin, Plastic & Reconstructive Surgern vol. 17, No. 1, 267-275 (Apr. 1956).
Goldman, et al., Lyophilized Veins as Arterial Interposition Allografts, Cryobiology 18, 306-312 (1981).
Gresham, Freeze-Drying of Human Tissue for Clinical Use, Cryobiology, vol. 1 No. 2 (1964).
Hayes, Skin Homografts--A Life-Saving Measure in Severely Burned Children, 22 Annual Session of American Association for Surgery of Trauma, Homestead, Hot Springs, VA (Oct. 1962).
Helenius, et al., Solubilization of Membranes by Detergents, Biochimica et Biophysica Acta, 415, 29-79 (1975).
Heiple, et al., A Comparative Study of the Healing Process Following Different Types of Bone Transplantation, Journal of Bone and Joint Surgery, vol. 45A No. 8, 1593-1616 (1963).
Hyatt, et al., New Methods for Preserving Bone, Skin and Blood Vessels, Postgraduate Medicine, vol. 12 No. 3 (Sep. 1952).
Kearney, et al., Cryopreservation of Skin Using a Murine Model: Validation of a Prognostic Viability Assay, Cryobiology 27, 24-30 (1990).
Konstantinow, et al., Skin Banking: A Simple Method for Cryopreservation of Split-Thickness Skin and Cultured Human Epidermal Keratinocytes, Annals of
Clarke Robert A.
Cryolife, Inc.
LandOfFree
Treated tissue for implantation and methods of preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Treated tissue for implantation and methods of preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Treated tissue for implantation and methods of preparation will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1866787