Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Eye prosthesis – Corneal implant
Patent
1992-01-21
1992-12-15
Isabella, David
Prosthesis (i.e., artificial body members), parts thereof, or ai
Eye prosthesis
Corneal implant
623 6, A61F 214
Patent
active
051713187
ABSTRACT:
Prosthetic devices are prepared for subepithelial implantation by coating their surfaces with a coating comprising crosslinked or uncrosslinked fibronectin. If the surface of the device comprises a material which does not normally bind fibronectin, it is pretreated, for example, by coating with poly(L-lysine). The coated prosthetic device is implanted by removing a portion of the epithelium, affixing the coated device to the subepithelial tissue optionally replacing all or part of the removed epithelium, and allowing new epithelial tissue to grow over and affix itself to the surface of the prosthetic device. The method of the invention can be used to implant contact lenses permanently beneath the epithelium of the cornea.
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Gibson David
Lerner Michael
Nordquist Robert
Reich Cary
Brittingham D. S.
Chiron Ophthalmics, Inc.
Isabella David
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