Trap vectors and gene trapping by using the same

Details Trap vectors and gene trapping by using the same Trap vectors and gene trapping by using the same

2007-12-25

2007-12-25

Qian, Celine (Department: 1636)

Chemistry: molecular biology and microbiology

Vector, per se

C435S325000, C536S024100

Reexamination Certificate

active

10030658

ABSTRACT:
A trap vector containing a loxP sequence composed of inverted repeat sequence 1, a spacer sequence and inverted repeat sequence 2 in this order, the loxP sequence being a mutant loxP wherein a part of the inverted repeat sequence 1 or 2 is mutated.

REFERENCES:
patent: 4237224 (1980-12-01), Cohen et al.
patent: 4468464 (1984-08-01), Cohen et al.
patent: 4736866 (1988-04-01), Leder et al.
patent: 4740470 (1988-04-01), Cohen et al.
patent: 4873191 (1989-10-01), Wagner et al.
patent: 4959317 (1990-09-01), Sauer
patent: 5300431 (1994-04-01), Pierce et al.
patent: 5378618 (1995-01-01), Sternberg et al.
patent: 5464764 (1995-11-01), Capecchi et al.
patent: 5487992 (1996-01-01), Capecchi et al.
patent: 5658772 (1997-08-01), Odell et al.
patent: 5789215 (1998-08-01), Berns et al.
patent: 5851808 (1998-12-01), Elledge et al.
patent: 5928914 (1999-07-01), Leboulch et al.
patent: 5994620 (1999-11-01), Schimenti et al.
patent: 6037125 (2000-03-01), Hasty
patent: 6057104 (2000-05-01), Hasty
patent: 6080576 (2000-06-01), Zambrowicz et al.
patent: 6777235 (2004-08-01), Ong et al.
patent: WO 94/24274 (1994-10-01), None
patent: WO 98/14614 (1998-04-01), None
patent: WO 98/20030 (1998-05-01), None
patent: WO 99/02719 (1999-01-01), None
patent: WO 99/02719 (1999-01-01), None
patent: WO 99/07389 (1999-02-01), None
patent: WO 99/10479 (1999-03-01), None
patent: WO 99/50426 (1999-10-01), None
patent: WO 00/09681 (2000-02-01), None
patent: WO 00/31236 (2000-06-01), None
Araki et al (1997, Nucleic Acid Research, vol. 25, No. 4, pp. 868-872).
Kuhn et al., Immunological Techniques, vol. 9, No. 2, pp. 183-188, (1997).
Albert et al., Plant Journal, vol. 7, No. 4, pp. 649-659, (1995).
Araki et al.; “Targeted Integration of DNA Using MutantIoxSites in Embryonic Stem Cells”; Nucleic Acids Research, vol. 25, No. 4, pp. 868-872, (1997).
Araki et al.; “Efficiency of Recombination by CRE Transient Expression in Embryonic Stem Cells: Comparison of Various Promoters”; Journal of Biochemistry, vol. 122, No. 5, pp. 977-982, (1997).
Irmgard et al.; “Selective Disruption of Genes Transiently Induced in Differentiating Mouse Embryonic Stem Cells by Using Gene Trap Mutagenesis ANS Site-Specific Recombination”; Molecular and Cellular Biology, vol. 18, No. 5, pp. 3081-3088, (1998).
Li et al.; “Generation of Mice With a 200-KB Amyloid Precursor Protein Gene Deletion by CRE Recombinase-Mediated Site-Specific Recombination in Embryonic Stem Cells”, Proceeding of National Acadmy of Sciences of the USA, vol. 93, No. 12, pp. 6158-6162, (1996).
Araki et al., Cellular and Molecular Biology, vol. 45, No. 5, pp. 737-750, (1999).
Oike et al., Human Molecular Genetics, vol. 8, No. 3, pp. 387-396, (1999).
Zambrowicz et al., Int. J. Dev. Biol. vol. 42, pp. 1025-1036, (1998).
Oike et al., Blood, vol. 93, No. 9, pp. 2771-2779, (1999).
Friedrich et al., Genes & Development, vol. 5, pp. 1513-1523, (1991).

Affiliated with

Also associated with

Rating

Trap vectors and gene trapping by using the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Trap vectors and gene trapping by using the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Trap vectors and gene trapping by using the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3897432