Transposase and method of gene modification

Details Transposase and method of gene modification Transposase and method of gene modification

2006-03-14

2008-12-23

Chen, Shin-Lin (Department: 1632)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S023100, C536S023500, C530S350000

Reexamination Certificate

active

07468430

ABSTRACT:
A transposase encoded by the Tol2 element; a polynucleotide encoding the same; a method of modifying the gene structure of a cell (preferably a vertebrate cell) by using the above protein; a method of modifying the function of a cell by modifying the gene structure thereof; and a cell having been modified in function by these methods. Also the structure of a cis element necessary in gene transfer is clarified and presented.

REFERENCES:
Deonarain, M., 1998, Expert Opin. Ther. Pat., vol. 8, pp. 53-69.
Verma et al., Sep. 1997, Nature, vol. 389, pp. 239-242.
Crystal, R., 1995, Science, vol. 270, p. 404-410.
Eck et al., 1996, Goodman & Gilman's The Pharmacological Basis of Therapeutics, McGraw-Hill, New York, p. 77-101.
Kawakami et al., Nov. 26, 1999, GenEmbl Accession No. AB032244, computer printout, p. 14-17.
Tsutsumi et al., directly submitted Aug. 11, 1999, GenEmbl Accession No. AB031079, computer printout pp. 17-19.
K. Kawakami et al.,Gene, 240: 239-244 (1999).
K. Kawakami et al.,Gene, 225: 17-22 (1998).
A. Koga et al.,Genbank, Acc. No. D84375 (1999).
A. Koga et al.,FEBS Letters, 461: 295-298 (1999).
A Koga et al.,Nature, 383: 30 (1996).
G. Luo,Proc. Natl. Acad. Sci. USA, 95: 10769-10773 (1998).
L. Zhang et al.,Nucleic Acids Research, 26 (16): 3687-3693 (1998).
A. Sherman et al,Nature Biotechnology, 16:1050-1053 (1998).
Z. Li et al.,Somatic Cell and Molecular Genetics, 24(6): 363-369 (1998).
E. Rubin et al,Proc. Natl. Acad. Sci USA96: 1645-1650 (1999).
K. Kawakami et al.,Gene, 240: 239-244 (1999), Database accession No. AB032244 (abstract only).
A. Koga et al.,Nature, 383: 30-30 (1996), Database accession No. Q98969 (abstract only).
Izsvak et al.,Biochemistry&Cell Biology, 75: 507-523 (1997).
GenEmbl Accession No. AB032244, Nov. 26, 1999, pp. 1-3.
SPTREMBL Accession Nos. Q98968, 98969, 98970, 98971, 1997, pp. 3-4.
Rudinger, 1976, Peptide Hormones, Parsons, University Park Press, Baltimore. p. 1-7.
Kaye et al., 1990, Proc. Natl. Acad. Sci. USA, vol. 87, pp. 6922-6926.
Skolnick et al., 2000, Trends in Biotech, vol. 18, pp. 34-39.
De Lorenzo, Victor, “Genetic Engineering Strategies for Environmental Applications,” Current Opinion in Biotechnology, vol, 3(3), pp. 227-231 (1992).

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