Transporter protein in mammal and utilization of the same

Details Transporter protein in mammal and utilization of the same Transporter protein in mammal and utilization of the same

2011-02-22

2011-02-22

Li, Ruixiang (Department: 1646)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

C530S350000

Reexamination Certificate

active

07892728

ABSTRACT:
The present invention provides a lipid membrane that contains a polypeptide consisting of the amino acid sequence of SEQ ID NO: 2, 4, 6, 8, or 22. Use of the present invention enables screening for a chemical which regulates excretion of a chemical and/or a waste. Furthermore, use of the present invention enables an arbitrary chemical to be tested for nephrotoxicity and/or hepatotoxicity.

REFERENCES:
patent: 2007/0105122 (2007-05-01), Ota et al.
patent: 2007/0224201 (2007-09-01), Wu et al.
patent: 2002191363 (2002-07-01), None
patent: 0234783 (2002-05-01), None
patent: 03089583 (2003-10-01), None
Otsuka et al., “A Human Transporter Protein That Mediates the Final Excretion Step for Toxic Organic Cations,” Proc. Natl. Acad. Sci. USA, vol. 102, No. 50, pp. 17923-17928, Dec. 2005.
Morita et al., “NorM, a Putative Multidrug Efflux Protein, of Vibrio Parahaemolyticus and Its Homolog inEscherichia coli,” Antimicrob Agents Chemother, vol. 42, No. 7, pp. 1778-1782, 1998.
Database SwissProt[online], Accession No. Q8KOH1, <<http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?81900833:CAGE—DDBJ:1966 641>> Jun. 1, 2003, Definition: 130013J15Rik protein.
Database SwissProt[online], Accession No. Q86VL8 <<http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?74727585:CAGE—DDBJ:5745 64>> Oct. 1, 2003, Definition: Hypothetical protein FLJ31196.
Database SwissProt[online], Accession No. Q8IV44 <<http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?74728032:CAGE—DDBJ:5750 17>> Jun. 1, 2003, Definition: FLJ31196 protein.
Database SwissProt[online], Accession No. Q96FL8 <<http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?74731723:CAGE—DDBJ:5787 35>> Jun. 1, 2003, Definition: Hypothetical protein FLJ10847.
Database SwissProt[online], Accession No. Q9NVA3 <<http://www.ncbi.nlm.nih.gov/entrez/viewerfcgi?74734474:CAGE—DDBJ:5815 02>> Jun. 1, 2003, Definition: Hypothetical protein FLJ10847.
Hvorup RN et al., “The Multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) Exporter Superfamily”, Eur. J. Biochem., vol. 270, No. 5, pp. 799-813, 2003.
International Preliminary Report on Patentability for PCT/JP2006/320409 dated Jun. 19, 2008.

Affiliated with

Also associated with

Rating

Transporter protein in mammal and utilization of the same does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transporter protein in mammal and utilization of the same, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transporter protein in mammal and utilization of the same will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2633718