Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure
Patent
1996-07-24
1998-12-29
Hutzell, Paula K.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
Molecular bilayer structure
424450, 424400, 424149, 546347, 514358, 514975, 514788, A61K 5100, A61M 3614
Patent
active
058536949
ABSTRACT:
The invention relates to new compounds with the general formula I for use as a tool to introduce macromolecules into cells. The invention further relates to compositions for introducing macromolecules into cells, comprising vesicles formed by at least one compound in a solvent. The macromolecule can be incorporated in the vesicles and/or bound to the vesicles or another aggregate of the new compounds. In a preferred embodiment at least one targeting molecule, for instance a (labelled) antibody, may further be attached to the vesicles. ##STR1##
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Engberts Jan Bernard Frederik Nicolaas
Hoekstra Dirk
Ruiters Marcel Herman Jozef
Van Der Woude Irene
Wagenaar Anno
Bakalyar Heather A.
Hutzell Paula K.
Rijksuniversiteit Groningen
Stichting Scheikundig Ondoerzoek in Nederland
Stitching Voor DeTechnische Wetenschappen
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