Transport vectors

Details Transport vectors Transport vectors

2006-12-26

2006-12-26

Canella, Karen A. (Department: 1642)

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

15 to 23 amino acid residues in defined sequence

C530S327000, C530S328000, C530S329000, C530S323000, C530S402000

Reexamination Certificate

active

07153931

ABSTRACT:
The invention relates to modified and truncated forms of the membrane transport vector penetratin. Such truncated forms include 7-mer peptides that may in themselves include further variation.

REFERENCES:
patent: 4847240 (1989-07-01), Ryser et al.
patent: 5043329 (1991-08-01), Lichtenberger
patent: 5179086 (1993-01-01), Flender
patent: 5580563 (1996-12-01), Tam
patent: 5888762 (1999-03-01), Joliot et al.
patent: 6025140 (2000-02-01), Langel et al.
patent: 6080724 (2000-06-01), Chassaing et al.
patent: 6472507 (2002-10-01), Fischer et al.
patent: 0751225 (1991-10-01), None
patent: 0485578 (1996-10-01), None
patent: 751225 (1997-01-01), None
patent: 2 340 121 (2000-02-01), None
patent: WO 91/18981 (1991-12-01), None
patent: WO 95/33766 (1995-12-01), None
patent: WO 95/34295 (1995-12-01), None
patent: WO 97/12912 (1997-04-01), None
patent: WO 97/19954 (1997-06-01), None
patent: WO 97/25070 (1997-07-01), None
patent: WO 98/13059 (1998-04-01), None
patent: WO 98/38861 (1998-09-01), None
patent: WO 98/56938 (1998-12-01), None
patent: WO 99/05302 (1999-02-01), None
patent: WO 99/11809 (1999-03-01), None
patent: WO 00/01417 (2000-01-01), None
Caplus Database Accession No. 165206, 1997.
Fischer et al (Journal of Peptide Research, 2000, vol. 55, pp. 163-172).
U.S. Appl. No. 10/210,660, Fischer et al.
Brugidou, J. et al. (1995) “The Retro-Inverso Form Of A Homeobox-Derived Short Peptide Is Rapidly Internalised By Cultured Neurones: A New Basis For An Efficient Intracellular Delivery System” Biochemical and Biophysical Research Communications, vol. 214, No. 2, pp. 685-693.
Derossi, Daniele et al. (1994) “The Third Helix of the Antennapedia Homeodomain Translocates Through Biological Membranes” The Journal of Biological Chemistry, vol. 269, No. 14, pp. 10444-10450.
Derossi, Daniele et al (1996) “Cell Internalization of the Third Helix of the Antennapedia Homeodomain Is Receptor-Independent” The Journal of Biological Chemistry, vol. 271, No. 30, pp. 18188-18193.
Plank, Christian (1999) “Branched Cationic Peptides For Gene Delivery: Role of Type and Number of Cationic Residues In Formation And In Vitro Activity of DNA Polyplexes” Human Gene Therapy, vol. 10, pp. 319-332.
Prochiantz, Alain (1996) “Getting Hydrophilic Compounds Into Cells: Lessons From Homeopeptides” Current Opinion in Neurobiology, vol. 6 , pp. 629-634.
Simmons, Carla G. (1997) “Synthesis And Membrane Permeability of PNA-Peptide Conjugates”, Bioorganic & Medicinal Chemistry Letters, vol. 7, No. 23, pp. 3001-3006.
Schutze-Redelmeier, Marie-Paule et al. (1996) “Introduction of Exogenous Antigens Into The MHC Class I Processing And Presentation Pathway By Drosophila Antennapedia Homeodomain Primes Cytotoxic T Cells In Vivo” The Journal of Immunologists, pp. 651-655.
Derossi D, et al. “Trojan peptides: the penetratin system for intracellular delivery.”Trends Cell Biol.Feb. 1998;8(2):84-7.
Fischer PM, et al. “Structure-activity relationship of truncated and substituted analogues of the intracellular delivery vector Penetratin”.J Pept Res.Feb. 2000;55(2):163-72.

Affiliated with

Also associated with

Rating

Transport vectors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transport vectors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transport vectors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3717916