Transplants for myocardial scars

Details Transplants for myocardial scars Transplants for myocardial scars

1998-06-19

2000-08-08

Elliott, George C.

Drug, bio-affecting and body treating compositions

Whole live micro-organism, cell, or virus containing

Genetically modified micro-organism, cell, or virus

435455, 435325, 435378, A61K 3534, C12N 1509, C12N 1585

Patent

active

060998326

ABSTRACT:
A method is provided for forming a graft in heart tissue which comprises the transplantation of cells chosen from cardiomyocytes, fibroblasts, smooth muscle cells, endothelial cells and skeletal myoblasts. The grafts are especially useful in treating scar tissue on the heart.

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Li et al., "In Vivo Survival and Function of Transplanted Rat Cardiomyocytes" Circulation Research 78:283-288 (1996).
Murry et al., "Skeletal Myobalst Transplantation for Repair of Myocardial Necrosis" J. Clin. Invest. 98:2512-2523 (1996).
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